Eleanor Brown of The Washington Post wrote that, ''Small Great Things' is the most important novel Jodi Picoult has ever written. The novel received positive and mixed reviews.

Rainn: The man who introduced Turk to white supremacy.

Marie: Ruth's boss at Mercy-West Haven Hospital.

Howard: Kennedy's assistant, helps to form a legal defense for the murder trial of Ruth.

Judge 'Thunder' Turner: The judge who presides over Ruth's court trials.

Jack DeNardi: An office clerk ('paper pusher') at the hospital, from whom Kennedy 'fishes' information.

Carla: A legal consultant for the hospital where Ruth works.

Lucille: A nurse who works alongside Ruth.

Corrine: A nurse who works alongside Ruth.

She is around Ruth's age and they are friends. Mina: The woman for whose family Ruth's mother works as a domestic servant.

Rachel: Adisa's birth name, which she changes as a young adult to Adisa.

Sam Hallowell: The man for whose family Ruth's mother works as a domestic servant.Wallace Mercy: A popular televangelist.Odette Lawton: The prosecutor for Ruth's case, an African-American woman.Francis: Brit's father, who is a white supremacist.Turk Bauer: A white supremacist with swastika tattoos.Ruth Jefferson: A twenty-year employed nurse at Mercy-West Haven Hospital who is accused of murder when an infant dies in her care.Picoult frequently employs an alternating multi-perspective narrative style in her novels, including My Sister's Keeper, Songs of the Humpback Whale, Sing You Home, Handle With Care, Change of Heart, House Rules, Lone Wolf, and The Storyteller. The story is told from the complex multiple racial perspectives of the principal characters, including the nurse, Ruth, Turk Bauer, the white supremacist father of the baby, and Kennedy McQuarrie, Ruth's attorney.

After the baby dies in her care, Ruth is charged with murder, and taken to court. Ruth is ordered not to touch or go near the baby of a white supremacist couple. The story concentrates on an African-American labor/delivery (L&D) nurse, Ruth Jefferson, in charge of newborns at a fictional Connecticut hospital. This is Picoult's first novel with an African American protagonist. Small Great Things is being adapted into a film starring Viola Davis and Julia Roberts. The book focuses on race in America and revolves around the protagonist, a delivery nurse, named Ruth Jefferson. Small Great Things (2016) is the twenty-fifth novel by American author Jodi Picoult.

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